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By Gregg Simonds
How ranchers can help halt E.coli
Through innovative new management practices, cow-calf producers can help reduce food-borne illness like E.coli and Salmonella.
When a food recall due to E. coli O157:H7 or other food-borne pathogens, like Salmonella or Listeria, grabs the headlines – it can shake consumer confidence in food products, which doesn’t bode well for the beef industry.

So, do ranchers have any ability to help enhance the safety of the beef they produce and help minimize the incidence of food-borne illness in beef?

Absolutely! Beef industry experts say that food safety starts at the ranch.

John Scanga, who has done extensive research on red meat safety and meat quality as an Extension meat scientist with Colorado State University, explains, saying,“E. coli O157:H7 is a pathogen that is prevalent across all environments, so an integrated approach from cow-calf to the packing plant to the consumer is necessary to help combat food-borne illness.”

Why is the ranch a logical place for pre-harvest control of E. coli?
Because the majority of U.S. cattle are handled by only a few packers, the industry has implemented food safety intervention strategies at that sector since they are easier to universally employ, explains Scanga.

Hazard Analysis Critical Control Points (HACCP) at the packing plant include a multi-faceted system of interventions to kill pathogenic organisms on the carcass such as steam vac, thermal pasteurization, pre-evisceration wash, and an organic acid wash.

However, while those methods have offered improved success, foodborne pathogens like E. coli O157:H7 continue to plague the meat industry. Thus, new emphasis is being placed on additional intervention strategies to reduce food-borne pathogenic bacterial populations in the live animal prior to slaughter.

“What we’ve learned about the E.coli O157:H7 organism is that it is really transferred from animal to animal, through water, nursing calves, etc.,” says Scanga. Therefore, he says there are a number of preharvest pathogen controls at the cow-calf level and at the feedlot that may help reduce the incidence of food-borne pathogens.

What are some specific management practices to help reduce foodborne pathogens at the cow-calf level?
Scanga cites research on two vaccines currently being field tested, as well as research on feeding probiotic supplements to reduce E. coli O157:H7 in the fecal matter of cattle.
Additionally, Scanga suggests management practices such as water tank sanitation and providing dry areas for cattle may aid in reducing food-borne pathogens. Biosecurity steps with feed may also be beneficial. For instance, using two different loaders to move manure and handle feed to prevent cross-contamination.

How do probiotic supplements work?
West Texas A&M epidemiologist Guy Loneragan explains that currently, Nutrition Physiology Corp. offers a product called Bovamine, which is the most widely studied probiotic product and on average has been shown to decrease the percentage of cattle testing positive for the E. coli O157 organism by 40 to 60%.

Loneragan says, “It clearly works, but it does not have a label-claim for reducing E. coli O157.” To be effective, the probiotic needs to be fed every day, so would be best suited to confined animals.

Another supplement product is Sodium chlorate. This chemical gets converted by certain bacteria, including E. coli O157 and Salmonella, to a toxic substrate, explains Loneragan. It can be developed to be delivered in feed or water and holds great promise, he says, and reports that a company is currently sponsoring it through the FDA approval process. So it is hoped that if all goes well, it will be available soon.

Another product being studied are specific strains of bacteriophages, which have been shown to prey on certain pathogens like E. coli O157, according to Loneragan. Certain bacteriophages have already been approved for application to tomatoes, and ready-to-eat products for Listeria, as well as to the surface of cattle for E. coli O157. “If these could be developed on a commercial scale for oral administration to cattle, it would be of great interest,” Loneragan says.

What about vaccination? Is that available?
Presently, Bioniche Animal Health and Epitopix – which has a cooperative agreement with AgriLabs – are in various stages of field trials and requesting a license for special vaccines developed to reduce shedding of E.coli O157:H7 [both companies] and Salmonella Newport [Epitopix]. Loneragan calls these “extremely promising products,” and says the advantage of a vaccine is that it could be used in a variety of production settings and fit into normal procedures.

Bioniche has just recently received a Permit to Release Veterinary Biologic in the U.S., which is a restricted conditional license to make it available.

Of the vaccine Loneragan says, “The product clearly works across a significant number of field trials and these data have been published and are compelling.” Loneragan adds that with the approval of the first license, it should facilitate the licensing process for other companies such as Epitopix.

What advice should ranchers heed as these new technologies become available for combating pathogens like E.coli and Salmonella?
Loneragan admits that none of these technologies alone will be a silver bullet for the industry, but each represents a hurdle in a multi-hurdle approach.

For example, Loneragan says, “Continued use of probiotic supplements like Bovamine is important but adding vaccines to certain situations or sodium chlorate before harvest will add hurdles that enhance beef safety at harvest and beyond.”

He says, “The goal is that efficacious preharvest interventions will decrease the percentage of cattle carrying E. coli O157 into plants; and decrease shedding into the environment and the opportunity for reinfection. These latter aspects of control are extremely valuable.”

Loneragan also emphasizes that different intervention technologies are needed so that they can suit varied production practices. Of the products outlined above he says, “These are all slightly different and some may be better suited to different production settings.”

Given the increased number of beef recalls due to E. coli O157 in 2007, Loneragan says it is critical that these preharvest interventions gain approval and begin to be applied within the industry.

“The industry is committed to eliminating this pathogen partly so we are not saddled with these recalls, but most importantly, it will be an important aid in helping producers supply consumers with the safest possible product,” Loneragan says.

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